pregnenediol disulfate (c21h34o8s2)* to x-21441

Numerator Metabolite

Metabolite Accession: GCST90199840
Name: pregnenediol disulfate (c21h34o8s2)*
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Denominator Metabolite

Metabolite Accession: GCST90200581
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs174548

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Clumped rQTL variant

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SNP Summary

Chr:
11
Beta (Ratio):
0.122
Position:
61571348
SE (Ratio):
0.015
Effect Allele:
G
Z-score (Ratio):
8.304
Reference Allele:
C
-log10(P):
-36.834
MAF:
0.309
Beta (Num):
0.046
Novel Locus:
Yes ✔️
SE (Num):
0.015
Beta (Den):
-0.076
SE (Den):
0.017
No CNV overlap
rQTL cluster:
62
Reaction Distance:
NA
Closest Genes:
FADS2 FADS1 FEN1 TMEM258 MYRF

Region: rs56148886

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
12
Beta (Ratio):
0.136
Position:
21334570
SE (Ratio):
0.016
Effect Allele:
C
Z-score (Ratio):
8.447
Reference Allele:
T
-log10(P):
-38.049
MAF:
0.231
Beta (Num):
0.101
Novel Locus:
No
SE (Num):
0.016
Beta (Den):
-0.035
SE (Den):
0.018
No CNV overlap
rQTL cluster:
52
Reaction Distance:
NA
Closest Genes:
SLCO1B1 RP11-125O5.2 SLCO1A2 SLCO1B7 LST3

Region: rs2011425

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.378
Position:
234627608
SE (Ratio):
0.025
Effect Allele:
G
Z-score (Ratio):
-15.341
Reference Allele:
T
-log10(P):
-120.631
MAF:
0.080
Beta (Num):
-0.016
Novel Locus:
No
SE (Num):
0.025
Beta (Den):
0.362
SE (Den):
0.028
No CNV overlap
rQTL cluster:
136
Reaction Distance:
NA
Closest Genes:
UGT1A10 UGT1A5 UGT1A8 UGT1A6 UGT1A4

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data