androstenediol (3beta,17beta) monosulfate (1) to x-21441

Numerator Metabolite

Structure of androstenediol (3beta,17beta) monosulfate (1)
Metabolite Accession: GCST90199872
Name: androstenediol (3beta,17beta) monosulfate (1)
Hmdb Id: HMDB0240429
Super Pathway: NA
Sub Pathway: NA
Inchikey: KMTOEENORMWLCF

Denominator Metabolite

Metabolite Accession: GCST90200581
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs41318029

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
-0.617
Position:
101590486
SE (Ratio):
0.062
Effect Allele:
A
Z-score (Ratio):
-9.926
Reference Allele:
G
-log10(P):
-51.795
MAF:
0.016
Beta (Num):
-0.133
Novel Locus:
No
SE (Num):
0.054
Beta (Den):
0.484
SE (Den):
0.061
No CNV overlap
rQTL cluster:
232
Reaction Distance:
NA
Closest Genes:
ABCC2 DNMBP CUTC COX15 ENTPD7

Region: rs72838138

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.649
Position:
101607901
SE (Ratio):
0.033
Effect Allele:
A
Z-score (Ratio):
19.634
Reference Allele:
G
-log10(P):
-195.962
MAF:
0.059
Beta (Num):
0.052
Novel Locus:
No
SE (Num):
0.029
Beta (Den):
-0.597
SE (Den):
0.033
No CNV overlap
rQTL cluster:
68
Reaction Distance:
NA
Closest Genes:
ABCC2 DNMBP CUTC COX15 ENTPD7

Region: rs3732218

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.396
Position:
234627304
SE (Ratio):
0.028
Effect Allele:
A
Z-score (Ratio):
-14.197
Reference Allele:
G
-log10(P):
-103.661
MAF:
0.082
Beta (Num):
-0.040
Novel Locus:
No
SE (Num):
0.024
Beta (Den):
0.356
SE (Den):
0.027
No CNV overlap
rQTL cluster:
136
Reaction Distance:
NA
Closest Genes:
UGT1A10 UGT1A5 UGT1A8 UGT1A6 UGT1A7

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data