etiocholanolone glucuronide to x-21364

Numerator Metabolite

Structure of etiocholanolone glucuronide
Metabolite Accession: GCST90199964
Name: etiocholanolone glucuronide
Hmdb Id: HMDB0004484
Super Pathway: NA
Sub Pathway: NA
Inchikey: VFUIRAVTUVCQTF

Denominator Metabolite

Metabolite Accession: GCST90200566
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs62142080

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.160
Position:
32182528
SE (Ratio):
0.016
Effect Allele:
C
Z-score (Ratio):
-9.722
Reference Allele:
T
-log10(P):
-49.771
MAF:
0.391
Beta (Num):
-0.112
Novel Locus:
No
SE (Num):
0.016
Beta (Den):
0.048
SE (Den):
0.015
No CNV overlap
rQTL cluster:
151
Reaction Distance:
NA
Closest Genes:
MEMO1 DPY30 SPAST SLC30A6 NLRC4

Region: rs1165196

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
6
Beta (Ratio):
-0.176
Position:
25813150
SE (Ratio):
0.016
Effect Allele:
G
Z-score (Ratio):
-10.942
Reference Allele:
A
-log10(P):
-62.488
MAF:
0.444
Beta (Num):
-0.050
Novel Locus:
No
SE (Num):
0.015
Beta (Den):
0.126
SE (Den):
0.015
No CNV overlap
rQTL cluster:
111
Reaction Distance:
NA
Closest Genes:
SLC17A1 SLC17A3 SLC17A4 HIST1H2BA HIST1H2AA

Region: rs148982377

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
7
Beta (Ratio):
-0.432
Position:
99075038
SE (Ratio):
0.045
Effect Allele:
C
Z-score (Ratio):
-9.659
Reference Allele:
T
-log10(P):
-49.151
MAF:
0.032
Beta (Num):
-0.304
Novel Locus:
No
SE (Num):
0.043
Beta (Den):
0.128
SE (Den):
0.040
No CNV overlap
rQTL cluster:
90
Reaction Distance:
NA
Closest Genes:
ZNF789 ZNF394 ATP5J2 ATP5J2-PTCD1 PTCD1

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data