dihomo-linolenoylcarnitine (c20:3n3 or 6)* to oleoylcarnitine (c18:1)

Numerator Metabolite

Metabolite Accession: GCST90200139
Name: dihomo-linolenoylcarnitine (c20:3n3 or 6)*
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Denominator Metabolite

Metabolite Accession: GCST90199774
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs968567

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Clumped rQTL variant

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SNP Summary

Chr:
11
Beta (Ratio):
0.293
Position:
61595564
SE (Ratio):
0.017
Effect Allele:
T
Z-score (Ratio):
17.060
Reference Allele:
C
-log10(P):
-148.595
MAF:
0.179
Beta (Num):
0.237
Novel Locus:
No
SE (Num):
0.020
Beta (Den):
-0.056
SE (Den):
0.020
No CNV overlap
rQTL cluster:
62
Reaction Distance:
NA
Closest Genes:
FADS1 FADS2 FEN1 TMEM258 MYRF

Region: rs2229738

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
11
Beta (Ratio):
0.263
Position:
68562328
SE (Ratio):
0.026
Effect Allele:
T
Z-score (Ratio):
10.259
Reference Allele:
C
-log10(P):
-55.191
MAF:
0.071
Beta (Num):
0.217
Novel Locus:
No
SE (Num):
0.029
Beta (Den):
-0.045
SE (Den):
0.029
No CNV overlap
rQTL cluster:
57
Reaction Distance:
NA
Closest Genes:
CPT1A MTL5 MRPL21 GAL IGHMBP2

LLM Analysis

Numerator Metabolite Explanation:

Fatty acid metabolism.1[1], 2[2]

Denominator Metabolite Explanation:

Fatty acid beta-oxidation.3[1], 4[2]

Ratio Explanation:

The provided information does not contain sufficient evidence to form a complete biological analysis.

Ratio Evidence:

metabolites unrelated

Gene Ratio Phenotype Relationship:

The provided information does not contain sufficient evidence to form a complete biological analysis.

Phenotype Driver:

none

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data