11beta-hydroxyandrosterone glucuronide to x-24494

Numerator Metabolite

Structure of 11beta-hydroxyandrosterone glucuronide
Metabolite Accession: GCST90200214
Name: 11beta-hydroxyandrosterone glucuronide
Hmdb Id: HMDB0010351
Super Pathway: NA
Sub Pathway: NA
Inchikey: BRPLOVMHAFXVOQ

Denominator Metabolite

Metabolite Accession: GCST90200635
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs72790679

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Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.946
Position:
31654155
SE (Ratio):
0.071
Effect Allele:
A
Z-score (Ratio):
-13.297
Reference Allele:
G
-log10(P):
-91.218
MAF:
0.017
Beta (Num):
-0.455
Novel Locus:
No
SE (Num):
0.057
Beta (Den):
0.491
SE (Den):
0.060
No CNV overlap
rQTL cluster:
150
Reaction Distance:
NA
Closest Genes:
XDH EHD3 CAPN14 GALNT14 MEMO1

Region: rs113017476

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Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.837
Position:
31989359
SE (Ratio):
0.051
Effect Allele:
A
Z-score (Ratio):
-16.435
Reference Allele:
G
-log10(P):
-138.085
MAF:
0.035
Beta (Num):
-0.420
Novel Locus:
No
SE (Num):
0.040
Beta (Den):
0.418
SE (Den):
0.044
No CNV overlap
rQTL cluster:
149
Reaction Distance:
NA
Closest Genes:
MEMO1 DPY30 SPAST XDH SLC30A6

Region: rs74364753

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Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.827
Position:
32693881
SE (Ratio):
0.075
Effect Allele:
G
Z-score (Ratio):
-11.060
Reference Allele:
C
-log10(P):
-63.804
MAF:
0.015
Beta (Num):
-0.417
Novel Locus:
No
SE (Num):
0.059
Beta (Den):
0.410
SE (Den):
0.063
No CNV overlap
rQTL cluster:
150
Reaction Distance:
NA
Closest Genes:
BIRC6 YIPF4 TTC27 NLRC4 SLC30A6

Region: rs113425774

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.381
Position:
33004063
SE (Ratio):
0.040
Effect Allele:
A
Z-score (Ratio):
-9.479
Reference Allele:
G
-log10(P):
-47.407
MAF:
0.058
Beta (Num):
-0.155
Novel Locus:
No
SE (Num):
0.031
Beta (Den):
0.226
SE (Den):
0.035
No CNV overlap
rQTL cluster:
149
Reaction Distance:
NA
Closest Genes:
TTC27 BIRC6 LTBP1 YIPF4 NLRC4

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data