2,3-dihydroxy-5-methylthio-4-pentenoate (dmtpa)* to x-15503

Numerator Metabolite

Structure of 2,3-dihydroxy-5-methylthio-4-pentenoate (dmtpa)*
Metabolite Accession: GCST90200233
Name: 2,3-dihydroxy-5-methylthio-4-pentenoate (dmtpa)*
Hmdb Id: HMDB0240388
Super Pathway: NA
Sub Pathway: NA
Inchikey: XMZBEAXQGSBWLG

Denominator Metabolite

Metabolite Accession: GCST90200543
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs56113850

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
19
Beta (Ratio):
0.110
Position:
41353107
SE (Ratio):
0.014
Effect Allele:
T
Z-score (Ratio):
8.145
Reference Allele:
C
-log10(P):
-35.508
MAF:
0.423
Beta (Num):
0.032
Novel Locus:
Yes ✔️
SE (Num):
0.014
Beta (Den):
-0.078
SE (Den):
0.014
No CNV overlap
rQTL cluster:
244
Reaction Distance:
NA
Closest Genes:
CTC-490E21.12 CYP2A6 CYP2A7 EGLN2 RAB4B-EGLN2

Region: rs1371516

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.194
Position:
143748793
SE (Ratio):
0.017
Effect Allele:
G
Z-score (Ratio):
-11.565
Reference Allele:
A
-log10(P):
-69.551
MAF:
0.211
Beta (Num):
-0.039
Novel Locus:
No
SE (Num):
0.017
Beta (Den):
0.154
SE (Den):
0.017
No CNV overlap
rQTL cluster:
144
Reaction Distance:
NA
Closest Genes:
KYNU ARHGAP15 LRP1B GTDC1 ZEB2

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data