pregnenetriol disulfate* to x-21441

Numerator Metabolite

Metabolite Accession: GCST90200238
Name: pregnenetriol disulfate*
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Denominator Metabolite

Metabolite Accession: GCST90200581
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs174548

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
11
Beta (Ratio):
0.117
Position:
61571348
SE (Ratio):
0.015
Effect Allele:
G
Z-score (Ratio):
7.845
Reference Allele:
C
-log10(P):
-33.069
MAF:
0.309
Beta (Num):
0.040
Novel Locus:
Yes ✔️
SE (Num):
0.015
Beta (Den):
-0.076
SE (Den):
0.017
No CNV overlap
rQTL cluster:
62
Reaction Distance:
NA
Closest Genes:
FADS2 FADS1 FEN1 TMEM258 MYRF

Region: rs2011425

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.524
Position:
234627608
SE (Ratio):
0.025
Effect Allele:
G
Z-score (Ratio):
-21.031
Reference Allele:
T
-log10(P):
-224.426
MAF:
0.080
Beta (Num):
-0.162
Novel Locus:
No
SE (Num):
0.026
Beta (Den):
0.362
SE (Den):
0.028
No CNV overlap
rQTL cluster:
136
Reaction Distance:
NA
Closest Genes:
UGT1A10 UGT1A5 UGT1A8 UGT1A6 UGT1A4

Region: rs6843382

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
4
Beta (Ratio):
-0.121
Position:
69953602
SE (Ratio):
0.014
Effect Allele:
G
Z-score (Ratio):
-8.740
Reference Allele:
A
-log10(P):
-40.597
MAF:
0.461
Beta (Num):
-0.045
Novel Locus:
Yes ✔️
SE (Num):
0.014
Beta (Den):
0.076
SE (Den):
0.016
No CNV overlap
rQTL cluster:
122
Reaction Distance:
NA
Closest Genes:
UGT2B7 UGT2B11 UGT2A3 UGT2B28 UGT2B10

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data