pregnenetriol sulfate* to x-21441

Numerator Metabolite

Structure of pregnenetriol sulfate*
Metabolite Accession: GCST90200241
Name: pregnenetriol sulfate*
Hmdb Id: HMDB0241920
Super Pathway: NA
Sub Pathway: NA
Inchikey: DENIQPHQUIGDJZ

Denominator Metabolite

Metabolite Accession: GCST90200581
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs72838129

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.625
Position:
101604481
SE (Ratio):
0.031
Effect Allele:
C
Z-score (Ratio):
20.302
Reference Allele:
T
-log10(P):
-209.327
MAF:
0.059
Beta (Num):
0.028
Novel Locus:
No
SE (Num):
0.027
Beta (Den):
-0.597
SE (Den):
0.033
No CNV overlap
rQTL cluster:
68
Reaction Distance:
NA
Closest Genes:
ABCC2 DNMBP CUTC COX15 ENTPD7

Region: rs174564

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Clumped rQTL variant

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SNP Summary

Chr:
11
Beta (Ratio):
0.122
Position:
61588305
SE (Ratio):
0.015
Effect Allele:
G
Z-score (Ratio):
7.943
Reference Allele:
A
-log10(P):
-33.858
MAF:
0.343
Beta (Num):
0.060
Novel Locus:
Yes ✔️
SE (Num):
0.014
Beta (Den):
-0.062
SE (Den):
0.016
No CNV overlap
rQTL cluster:
62
Reaction Distance:
NA
Closest Genes:
FADS1 FADS2 FEN1 TMEM258 MYRF

Region: rs2011425

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Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.559
Position:
234627608
SE (Ratio):
0.026
Effect Allele:
G
Z-score (Ratio):
-21.225
Reference Allele:
T
-log10(P):
-228.542
MAF:
0.080
Beta (Num):
-0.197
Novel Locus:
No
SE (Num):
0.024
Beta (Den):
0.362
SE (Den):
0.028
No CNV overlap
rQTL cluster:
136
Reaction Distance:
NA
Closest Genes:
UGT1A10 UGT1A5 UGT1A8 UGT1A6 UGT1A4

Region: rs56217918

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
4
Beta (Ratio):
-0.122
Position:
69955643
SE (Ratio):
0.015
Effect Allele:
T
Z-score (Ratio):
-8.289
Reference Allele:
C
-log10(P):
-36.712
MAF:
0.461
Beta (Num):
-0.044
Novel Locus:
Yes ✔️
SE (Num):
0.013
Beta (Den):
0.078
SE (Den):
0.016
No CNV overlap
rQTL cluster:
122
Reaction Distance:
NA
Closest Genes:
UGT2B7 UGT2B11 UGT2A3 UGT2B28 UGT2B10

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data