quinolinate to x-15503

Numerator Metabolite

Structure of quinolinate
Metabolite Accession: GCST90200348
Name: quinolinate
Hmdb Id: HMDB0000232
Super Pathway: NA
Sub Pathway: NA
Inchikey: GJAWHXHKYYXBSV

Denominator Metabolite

Metabolite Accession: GCST90200543
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs61825638

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
1
Beta (Ratio):
-0.353
Position:
241713402
SE (Ratio):
0.017
Effect Allele:
T
Z-score (Ratio):
-20.534
Reference Allele:
C
-log10(P):
-214.063
MAF:
0.246
Beta (Num):
-0.143
Novel Locus:
No
SE (Num):
0.017
Beta (Den):
0.210
SE (Den):
0.016
No CNV overlap
rQTL cluster:
227
Reaction Distance:
NA
Closest Genes:
KMO FH OPN3 CHML WDR64

Region: rs56113850

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
19
Beta (Ratio):
0.118
Position:
41353107
SE (Ratio):
0.015
Effect Allele:
T
Z-score (Ratio):
7.907
Reference Allele:
C
-log10(P):
-33.569
MAF:
0.423
Beta (Num):
0.040
Novel Locus:
Yes ✔️
SE (Num):
0.014
Beta (Den):
-0.078
SE (Den):
0.014
No CNV overlap
rQTL cluster:
244
Reaction Distance:
NA
Closest Genes:
CTC-490E21.12 CYP2A6 CYP2A7 EGLN2 RAB4B-EGLN2

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data