androsterone glucuronide to x-24494

Numerator Metabolite

Structure of androsterone glucuronide
Metabolite Accession: GCST90200688
Name: androsterone glucuronide
Hmdb Id: HMDB0002829
Super Pathway: NA
Sub Pathway: NA
Inchikey: VFUIRAVTUVCQTF

Denominator Metabolite

Metabolite Accession: GCST90200635
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs112881196

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Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.760
Position:
31982811
SE (Ratio):
0.052
Effect Allele:
G
Z-score (Ratio):
-14.590
Reference Allele:
C
-log10(P):
-109.344
MAF:
0.034
Beta (Num):
-0.338
Novel Locus:
No
SE (Num):
0.037
Beta (Den):
0.422
SE (Den):
0.044
No CNV overlap
rQTL cluster:
149
Reaction Distance:
NA
Closest Genes:
MEMO1 DPY30 SPAST XDH SLC30A6

Region: rs72796850

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.785
Position:
32268286
SE (Ratio):
0.075
Effect Allele:
C
Z-score (Ratio):
-10.427
Reference Allele:
A
-log10(P):
-56.936
MAF:
0.015
Beta (Num):
-0.314
Novel Locus:
No
SE (Num):
0.054
Beta (Den):
0.471
SE (Den):
0.063
No CNV overlap
rQTL cluster:
150
Reaction Distance:
NA
Closest Genes:
DPY30 SPAST MEMO1 SLC30A6 NLRC4

Region: rs113425774

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
2
Beta (Ratio):
-0.373
Position:
33004063
SE (Ratio):
0.041
Effect Allele:
A
Z-score (Ratio):
-9.126
Reference Allele:
G
-log10(P):
-44.091
MAF:
0.058
Beta (Num):
-0.146
Novel Locus:
No
SE (Num):
0.028
Beta (Den):
0.226
SE (Den):
0.035
No CNV overlap
rQTL cluster:
149
Reaction Distance:
NA
Closest Genes:
TTC27 BIRC6 LTBP1 YIPF4 NLRC4

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data