5alpha-pregnan-3beta,20alpha-diol disulfate to x-21441

Numerator Metabolite

Structure of 5alpha-pregnan-3beta,20alpha-diol disulfate
Metabolite Accession: GCST90199838
Name: 5alpha-pregnan-3beta,20alpha-diol disulfate
Hmdb Id: HMDB0094650
Super Pathway: NA
Sub Pathway: NA
Inchikey: LSQGWMYMIHQKSA

Denominator Metabolite

Metabolite Accession: GCST90200581
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs17134531

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.184
Position:
5246085
SE (Ratio):
0.024
Effect Allele:
A
Z-score (Ratio):
7.580
Reference Allele:
G
-log10(P):
-30.995
MAF:
0.149
Beta (Num):
0.102
Novel Locus:
Yes ✔️
SE (Num):
0.022
Beta (Den):
-0.082
SE (Den):
0.022
No CNV overlap
rQTL cluster:
76
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 AKR1C2

Region: rs4881413

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.182
Position:
5258450
SE (Ratio):
0.024
Effect Allele:
T
Z-score (Ratio):
7.491
Reference Allele:
G
-log10(P):
-30.316
MAF:
0.150
Beta (Num):
0.103
Novel Locus:
Yes ✔️
SE (Num):
0.022
Beta (Den):
-0.079
SE (Den):
0.022
No CNV overlap
rQTL cluster:
217
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs2151901

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.182
Position:
5262965
SE (Ratio):
0.024
Effect Allele:
C
Z-score (Ratio):
7.493
Reference Allele:
A
-log10(P):
-30.332
MAF:
0.150
Beta (Num):
0.102
Novel Locus:
Yes ✔️
SE (Num):
0.022
Beta (Den):
-0.079
SE (Den):
0.022
No CNV overlap
rQTL cluster:
285
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data