3b-hydroxy-5-cholenoic acid to x-12851

Numerator Metabolite

Structure of 3b-hydroxy-5-cholenoic acid
Metabolite Accession: GCST90199933
Name: 3b-hydroxy-5-cholenoic acid
Hmdb Id: HMDB0000308
Super Pathway: NA
Sub Pathway: NA
Inchikey: HIAJCGFYHIANNA

Denominator Metabolite

Metabolite Accession: GCST90200514
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs10426201

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
19
Beta (Ratio):
0.236
Position:
48384749
SE (Ratio):
0.023
Effect Allele:
G
Z-score (Ratio):
10.421
Reference Allele:
A
-log10(P):
-56.875
MAF:
0.168
Beta (Num):
0.161
Novel Locus:
No
SE (Num):
0.023
Beta (Den):
-0.075
SE (Den):
0.022
No CNV overlap
rQTL cluster:
7
Reaction Distance:
NA
Closest Genes:
SULT2A1 TPRX2P CRX TPRX1 BSPH1

Region: rs147464959

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
19
Beta (Ratio):
0.801
Position:
59010910
SE (Ratio):
0.085
Effect Allele:
G
Z-score (Ratio):
9.428
Reference Allele:
A
-log10(P):
-46.920
MAF:
0.011
Beta (Num):
0.523
Novel Locus:
Yes ✔️
SE (Num):
0.083
Beta (Den):
-0.277
SE (Den):
0.084
No CNV overlap
rQTL cluster:
256
Reaction Distance:
NA
Closest Genes:
SLC27A5 ZBTB45 ZNF446 ZNF324 ZNF324B

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data