x-21353 to dodecadienoate (12:2)*

Numerator Metabolite

Metabolite Accession: GCST90200567
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Denominator Metabolite

Metabolite Accession: GCST90200190
Name: dodecadienoate (12:2)*
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs35259237

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Clumped rQTL variant

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SNP Summary

Chr:
14
Beta (Ratio):
0.309
Position:
73890837
SE (Ratio):
0.037
Effect Allele:
A
Z-score (Ratio):
8.255
Reference Allele:
C
-log10(P):
-36.427
MAF:
0.013
Beta (Num):
-0.065
Novel Locus:
No
SE (Num):
0.065
Beta (Den):
-0.374
SE (Den):
0.064
No CNV overlap
rQTL cluster:
45
Reaction Distance:
NA
Closest Genes:
NUMB HEATR4 ACOT1 ACOT2 PAPLN

Region: rs151154986

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
14
Beta (Ratio):
0.647
Position:
74040136
SE (Ratio):
0.026
Effect Allele:
A
Z-score (Ratio):
25.340
Reference Allele:
G
-log10(P):
-324.514
MAF:
0.030
Beta (Num):
0.042
Novel Locus:
No
SE (Num):
0.044
Beta (Den):
-0.605
SE (Den):
0.044
No CNV overlap
rQTL cluster:
44
Reaction Distance:
NA
Closest Genes:
ACOT2 HEATR4 ACOT4 ACOT1 ACOT6

Region: rs34713291

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
16
Beta (Ratio):
-0.140
Position:
2300206
SE (Ratio):
0.012
Effect Allele:
G
Z-score (Ratio):
-11.369
Reference Allele:
T
-log10(P):
-67.292
MAF:
0.148
Beta (Num):
0.022
Novel Locus:
No
SE (Num):
0.021
Beta (Den):
0.162
SE (Den):
0.021
No CNV overlap
rQTL cluster:
35
Reaction Distance:
NA
Closest Genes:
ECI1 RNPS1 AC009065.1 DNASE1L2 E4F1

Region: rs619873

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
6
Beta (Ratio):
-0.088
Position:
4107455
SE (Ratio):
0.009
Effect Allele:
G
Z-score (Ratio):
-9.283
Reference Allele:
A
-log10(P):
-45.552
MAF:
0.314
Beta (Num):
0.002
Novel Locus:
Yes ✔️
SE (Num):
0.016
Beta (Den):
0.089
SE (Den):
0.016
No CNV overlap
rQTL cluster:
113
Reaction Distance:
NA
Closest Genes:
C6orf201 ECI2 FAM217A PRPF4B C6ORF50

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data