epiandrosterone sulfate to x-24947

Numerator Metabolite

Structure of epiandrosterone sulfate
Metabolite Accession: GCST90199752
Name: epiandrosterone sulfate
Hmdb Id: HMDB0062657
Super Pathway: NA
Sub Pathway: NA
Inchikey: ZMITXKRGXGRMKS

Denominator Metabolite

Metabolite Accession: GCST90200651
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs4881413

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.166
Position:
5258450
SE (Ratio):
0.020
Effect Allele:
T
Z-score (Ratio):
8.146
Reference Allele:
G
-log10(P):
-35.515
MAF:
0.150
Beta (Num):
0.087
Novel Locus:
Yes ✔️
SE (Num):
0.020
Beta (Den):
-0.079
SE (Den):
0.022
No CNV overlap
rQTL cluster:
217
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs17134601

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.168
Position:
5261175
SE (Ratio):
0.020
Effect Allele:
G
Z-score (Ratio):
8.248
Reference Allele:
A
-log10(P):
-36.368
MAF:
0.149
Beta (Num):
0.087
Novel Locus:
Yes ✔️
SE (Num):
0.020
Beta (Den):
-0.081
SE (Den):
0.022
No CNV overlap
rQTL cluster:
76
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs2151901

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
0.168
Position:
5262965
SE (Ratio):
0.020
Effect Allele:
C
Z-score (Ratio):
8.201
Reference Allele:
A
-log10(P):
-35.969
MAF:
0.150
Beta (Num):
0.088
Novel Locus:
Yes ✔️
SE (Num):
0.020
Beta (Den):
-0.080
SE (Den):
0.022
No CNV overlap
rQTL cluster:
285
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs72818679

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
-0.269
Position:
96789135
SE (Ratio):
0.022
Effect Allele:
G
Z-score (Ratio):
-12.013
Reference Allele:
A
-log10(P):
-74.871
MAF:
0.120
Beta (Num):
-0.069
Novel Locus:
No
SE (Num):
0.022
Beta (Den):
0.200
SE (Den):
0.024
No CNV overlap
rQTL cluster:
70
Reaction Distance:
NA
Closest Genes:
CYP2C8 CYP2C9 C10orf129 CYP2C19 PDLIM1

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data