Infomap Cluster 70

Metabolite Network

mQTL individually significant in locus
Novel rQTL
Known rQTL

Aggregated Cluster Evidence

Significant GTEx eQTL Colocalization (P-alpha < 5e-5)

Tissue Gene P(alpha) Associated Metabolites
Heart Left Ventricle NFATC3 1.10e-05 androstenediol (3alpha, 17alpha) monosulfate (3)metabolonic lactone sulfate
Whole Blood SLC7A6 1.54e-05 androstenediol (3alpha, 17alpha) monosulfate (3)metabolonic lactone sulfate
Thyroid PLA2G15 3.73e-05 androstenediol (3alpha, 17alpha) monosulfate (3)metabolonic lactone sulfate

Genomic Context

Displaying 19 SNPs on Chr 10 for Cluster 70.

Novel rQTL (▲)
Known rQTL (▲)

Cluster Summary

15

Metabolite Ratios (rQTLs)

29

Total Unique Metabolites

7

Unnamed Metabolites

Ratios in Cluster 70

Ratio Name Novel in Cluster Driven By
16a-hydroxy dhea 3-sulfate to DHEAS No
16a-hydroxy dhea 3-sulfate to x-21470 No
21-hydroxypregnenolone disulfate to 16a-hydroxy dhea 3-sulfate No
21-hydroxypregnenolone disulfate to x-24546 No
5alpha-androstan-3alpha,17alpha-diol monosulfate to x-24947 No
5alpha-androstan-3alpha,17beta-diol monosulfate (1) to x-24546 No
5alpha-androstan-3alpha,17beta-diol monosulfate (1) to x-24947 No
5alpha-androstan-3beta,17beta-diol disulfate to x-24546 No
5alpha-androstan-3beta,17beta-diol disulfate to x-24947 No Denominator
5alpha-androstan-3beta,17beta-diol monosulfate (2) to x-24546 No
5alpha-androstan-3beta,17beta-diol monosulfate (2) to x-24947 No
5alpha-pregnan-3beta,20alpha-diol disulfate to 16a-hydroxy dhea 3-sulfate No
5alpha-pregnan-3beta,20alpha-diol disulfate to x-24546 No
5alpha-pregnan-3beta,20alpha-diol disulfate to x-24947 No
androstenediol (3alpha, 17alpha) monosulfate (3) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3alpha, 17alpha) monosulfate (3) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3alpha, 17alpha) monosulfate (3) to x-24546 No
androstenediol (3alpha, 17alpha) monosulfate (3) to x-24556 No
androstenediol (3alpha, 17alpha) monosulfate (3) to x-24947 No
androstenediol (3beta,17beta) disulfate (1) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) disulfate (1) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3beta,17beta) disulfate (1) to x-24546 No
androstenediol (3beta,17beta) disulfate (1) to x-24947 No
androstenediol (3beta,17beta) disulfate (2) to x-24546 No
androstenediol (3beta,17beta) disulfate (2) to x-24947 No
androstenediol (3beta,17beta) monosulfate (1) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) monosulfate (1) to x-24546 No
androstenediol (3beta,17beta) monosulfate (1) to x-24947 No
androstenediol (3beta,17beta) monosulfate (2) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) monosulfate (2) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3beta,17beta) monosulfate (2) to x-24546 No
androstenediol (3beta,17beta) monosulfate (2) to x-24947 No
androsterone sulfate to x-24947 No
epiandrosterone sulfate to x-24947 No
glycine conjugate of c10h14o2 (1)* to x-11787 No
metabolonic lactone sulfate to 5alpha-androstan-3beta,17beta-diol disulfate No
metabolonic lactone sulfate to androstenediol (3alpha, 17alpha) monosulfate (3) No
pregnenediol disulfate (c21h34o8s2)* to 16a-hydroxy dhea 3-sulfate No
pregnenediol disulfate (c21h34o8s2)* to x-24546 No
pregnenediol disulfate (c21h34o8s2)* to x-24947 No
pregnenediol sulfate (c21h34o5s)* to 16a-hydroxy dhea 3-sulfate No
pregnenediol sulfate (c21h34o5s)* to x-24546 No
pregnenetriol disulfate* to 16a-hydroxy dhea 3-sulfate No
pregnenetriol disulfate* to x-24546 No
pregnenetriol disulfate* to x-24947 No
pregnenolone sulfate to x-24546 No
x-11308 to x-11787 No
x-17654 to x-11787 No
x-24546 to DHEAS No
x-24546 to x-21470 No
x-24947 to DHEAS No