n6,n6-dimethyllysine to x-12112

Numerator Metabolite

Structure of n6,n6-dimethyllysine
Metabolite Accession: GCST90200696
Name: n6,n6-dimethyllysine
Hmdb Id: HMDB0013287
Super Pathway: NA
Sub Pathway: NA
Inchikey: XXEWFEBMSGLYBY

Denominator Metabolite

Metabolite Accession: GCST90200708
Name: NA
Hmdb Id: NA
Super Pathway: NA
Sub Pathway: NA
Inchikey: NA

Associated Genomic Regions

Region: rs77697233

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Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
-0.163
Position:
5246125
SE (Ratio):
0.014
Effect Allele:
T
Z-score (Ratio):
-11.750
Reference Allele:
C
-log10(P):
-71.723
MAF:
0.149
Beta (Num):
0.005
Novel Locus:
No
SE (Num):
0.022
Beta (Den):
0.168
SE (Den):
0.022
No CNV overlap
rQTL cluster:
76
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 AKR1C2

Region: rs4881413

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
-0.161
Position:
5258450
SE (Ratio):
0.014
Effect Allele:
T
Z-score (Ratio):
-11.650
Reference Allele:
G
-log10(P):
-70.550
MAF:
0.150
Beta (Num):
0.008
Novel Locus:
No
SE (Num):
0.022
Beta (Den):
0.169
SE (Den):
0.022
No CNV overlap
rQTL cluster:
217
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs2151901

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
10
Beta (Ratio):
-0.161
Position:
5262965
SE (Ratio):
0.014
Effect Allele:
C
Z-score (Ratio):
-11.604
Reference Allele:
A
-log10(P):
-70.011
MAF:
0.150
Beta (Num):
0.008
Novel Locus:
No
SE (Num):
0.022
Beta (Den):
0.169
SE (Den):
0.022
No CNV overlap
rQTL cluster:
285
Reaction Distance:
NA
Closest Genes:
AKR1C4 AKR1CL1 AKR1C3 UCN3 TUBAL3

Region: rs10418164

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
19
Beta (Ratio):
0.100
Position:
33411139
SE (Ratio):
0.010
Effect Allele:
T
Z-score (Ratio):
9.859
Reference Allele:
G
-log10(P):
-51.129
MAF:
0.391
Beta (Num):
-0.014
Novel Locus:
No
SE (Num):
0.016
Beta (Den):
-0.114
SE (Den):
0.016
No CNV overlap
rQTL cluster:
9
Reaction Distance:
NA
Closest Genes:
CEP89 SLC7A9 C19orf40 RHPN2 TDRD12

Region: rs662138

Click a 'Plot' button in the tables to the right to view a locus plot here.

Clumped rQTL variant

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SNP Summary

Chr:
6
Beta (Ratio):
0.159
Position:
160564476
SE (Ratio):
0.013
Effect Allele:
G
Z-score (Ratio):
12.267
Reference Allele:
C
-log10(P):
-77.985
MAF:
0.175
Beta (Num):
0.037
Novel Locus:
Yes ✔️
SE (Num):
0.020
Beta (Den):
-0.122
SE (Den):
0.020
No CNV overlap
rQTL cluster:
97
Reaction Distance:
NA
Closest Genes:
SLC22A1 SLC22A2 IGF2R SLC22A3 MAS1

LLM Analysis

Not available.

Downloads

Download the full rQTL summary statistics file for this metabolite ratio. Data contains the loci listed here. For each SNP (chromosome, effect_allele, reference_allele, pos_name, position) these columns contain the summary statistics of the ratio (beta, pgain, pval, se, z), the numerator metabolite (beta_1, pval_1, n_iids_1, effect_allele_frequency_1, se_1, z_1) and the denominator metabolite (beta_2, pval_2, n_iids_2, effect_allele_frequency_2, se_2, z_2)

Download rQTL Data