Infomap Cluster 132

Metabolite Network

mQTL individually significant in locus
Novel rQTL
Known rQTL

Aggregated Cluster Evidence

Significant GTEx eQTL Colocalization (P-alpha < 5e-5)

Tissue Gene P(alpha) Associated Metabolites
Heart Left Ventricle NFATC3 1.10e-05 1-palmitoyl-2-linoleoyl-gpe (16:0/18:2)1-palmitoyl-2-oleoyl-gpe (16:0/18:1)
Whole Blood SLC7A6 1.54e-05 1-palmitoyl-2-linoleoyl-gpe (16:0/18:2)1-palmitoyl-2-oleoyl-gpe (16:0/18:1)
Thyroid PLA2G15 3.73e-05 1-palmitoyl-2-linoleoyl-gpe (16:0/18:2)1-palmitoyl-2-oleoyl-gpe (16:0/18:1)

Genomic Context

Displaying 7 SNPs on Chr 3 for Cluster 132.

Novel rQTL (▲)
Known rQTL (▲)

Cluster Summary

20

Metabolite Ratios (rQTLs)

17

Total Unique Metabolites

0

Unnamed Metabolites

Ratios in Cluster 132

Ratio Name Novel in Cluster Driven By
1-linoleoyl-gpe (18:2)* to 1-oleoyl-gpe (18:1) Yes
1-oleoyl-gpe (18:1) to 1-linoleoyl-gpc (18:2) Yes
1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* to 1-oleoyl-gpe (18:1) Yes
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-oleoyl-2-arachidonoyl-gpe (18:1/20:4)* No
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-palmitoyl-2-arachidonoyl-gpe (16:0/20:4)* No Numerator
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* No
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-palmitoyl-2-docosahexaenoyl-gpe (16:0/22:6)* No
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-palmitoyl-2-linoleoyl-gpe (16:0/18:2) No
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-stearoyl-2-arachidonoyl-gpe (18:0/20:4) No
1-palmitoyl-2-oleoyl-gpe (16:0/18:1) to 1-stearoyl-2-linoleoyl-gpe (18:0/18:2)* No
1-palmitoyl-2-oleoyl-gpi (16:0/18:1)* to 1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* No
1-stearoyl-2-linoleoyl-gpe (18:0/18:2)* to 1-stearoyl-2-oleoyl-gpe (18:0/18:1) No
1-stearoyl-2-oleoyl-gpc (18:0/18:1) to 1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* Yes
1-stearoyl-2-oleoyl-gpe (18:0/18:1) to 1-oleoyl-2-linoleoyl-gpe (18:1/18:2)* No
1-stearoyl-2-oleoyl-gpe (18:0/18:1) to 1-palmitoyl-2-arachidonoyl-gpe (16:0/20:4)* No
1-stearoyl-2-oleoyl-gpe (18:0/18:1) to 1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* No
1-stearoyl-2-oleoyl-gpe (18:0/18:1) to 1-palmitoyl-2-linoleoyl-gpe (16:0/18:2) No
1-stearoyl-2-oleoyl-gpe (18:0/18:1) to 1-stearoyl-2-arachidonoyl-gpe (18:0/20:4) No
1-stearoyl-2-oleoyl-gpi (18:0/18:1)* to 1-palmitoyl-2-arachidonoyl-gpi (16:0/20:4)* No
1-stearoyl-gpe (18:0) to 1-oleoyl-gpe (18:1) Yes