Infomap Cluster 89

Metabolite Network

mQTL individually significant in locus
Novel rQTL
Known rQTL

Aggregated Cluster Evidence

Significant GTEx eQTL Colocalization (P-alpha < 5e-5)

Tissue Gene P(alpha) Associated Metabolites
Heart Left Ventricle NFATC3 1.10e-05 andro steroid monosulfate c19h28o6s (1)*androstenediol (3beta,17beta) monosulfate (1)
Whole Blood SLC7A6 1.54e-05 andro steroid monosulfate c19h28o6s (1)*androstenediol (3beta,17beta) monosulfate (1)
Thyroid PLA2G15 3.73e-05 andro steroid monosulfate c19h28o6s (1)*androstenediol (3beta,17beta) monosulfate (1)

Genomic Context

Displaying 1 SNPs on Chr 7 for Cluster 89.

Novel rQTL (▲)
Known rQTL (▲)

Cluster Summary

23

Metabolite Ratios (rQTLs)

14

Total Unique Metabolites

0

Unnamed Metabolites

Ratios in Cluster 89

Ratio Name Novel in Cluster Driven By
16a-hydroxy dhea 3-sulfate to androsterone sulfate No
16a-hydroxy dhea 3-sulfate to DHEAS No
16a-hydroxy dhea 3-sulfate to epiandrosterone sulfate No
5alpha-androstan-3alpha,17beta-diol monosulfate (1) to 16a-hydroxy dhea 3-sulfate No
5alpha-androstan-3alpha,17beta-diol monosulfate (1) to andro steroid monosulfate c19h28o6s (1)* No
5alpha-androstan-3beta,17beta-diol disulfate to 16a-hydroxy dhea 3-sulfate No Denominator, Numerator
5alpha-androstan-3beta,17beta-diol disulfate to andro steroid monosulfate c19h28o6s (1)* No
5alpha-androstan-3beta,17beta-diol disulfate to tauro-beta-muricholate No
5alpha-androstan-3beta,17beta-diol monosulfate (2) to 16a-hydroxy dhea 3-sulfate No
5alpha-androstan-3beta,17beta-diol monosulfate (2) to andro steroid monosulfate c19h28o6s (1)* No
5alpha-androstan-3beta,17beta-diol monosulfate (2) to glyco-beta-muricholate** No
andro steroid monosulfate c19h28o6s (1)* to DHEAS No
andro steroid monosulfate c19h28o6s (1)* to epiandrosterone sulfate No
androstenediol (3alpha, 17alpha) monosulfate (3) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3alpha, 17alpha) monosulfate (3) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3beta,17beta) disulfate (1) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) disulfate (1) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3beta,17beta) monosulfate (1) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) monosulfate (1) to andro steroid monosulfate c19h28o6s (1)* No
androstenediol (3beta,17beta) monosulfate (2) to 16a-hydroxy dhea 3-sulfate No
androstenediol (3beta,17beta) monosulfate (2) to andro steroid monosulfate c19h28o6s (1)* No
tauro-beta-muricholate to 5alpha-androstan-3beta,17beta-diol monosulfate (2) No
tauro-beta-muricholate to androstenediol (3alpha, 17alpha) monosulfate (3) No